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Time-dependent diffusion in undulating thin fibers: Impact on axon diameter estimation
2019
NMR in Biomedicine
Diffusion MRI may enable non-invasive mapping of axonal microstructure. Most approaches infer axon diameters from effects of time-dependent diffusion on the diffusion-weighted MR signal by modeling axons as straight cylinders. Axons do not, however, propagate in straight trajectories, and so far the impact of the axonal trajectory on diameter estimation has been insufficiently investigated. Here, we employ a toy model of axons, which we refer to as the undulating thin fiber model, to analyze
doi:10.1002/nbm.4187
pmid:31868995
pmcid:PMC7027526
fatcat:f7jxi3legrg5fmjnks42k7fcx4