A 69-year old woman was admitted because of nausea and vomiting. On admission she was slightly depressed. Then she gradually became delirious, and leresis, paranoia and confusion developed. On the 52nd hospital day, sudden generalized seizure developed and she was transfered to the ICU. Physical examination revealed a comatose state (JCS III-200), conjugate deviation to the right, right hemiparesis, exophthalmos and struma. Laboratory data confirmed hyperthyroidism, and she was diagnosed as

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... ng a thyroid crisis. In addition to the administration of Lugol's solution and thiamazole, she was treated with epidural block in order to restrain sympathetic hyperactivity. After 3 days she recovered from the coma and the hemiparesis.