Extensive Polyostotic Fibrous Dysplasia Associated with DTC Evaluated With 99mtc- MDP and 131I Whole Body Scan
Journal of Endocrinology and Thyroid Research
A 45-year-old female patients with differentiated thyroid carcinoma (DTC) was admitted to our hospital for 131I treatment. By medical examination, we found that the patient walked with a limb. The thyroglobulin level at that time was 1.51 ug/L and TSH: 30.45mU/L. In order to exclude bone metastases, 99mTc-MDP whole body scan was performed ( Figure 1 ). The result showed that sphenoid bone, multiple ribs, limb bone (including humerus, tibia, fibula, femur) had intense uptake (A: anterior view,
... posterior view). The digital X ray (DR) and computed tomography (CT) found that multiple ground-glass opacity and expansion in limb bone, which indicated polyostotic fibrous dysplasia (C-F). Four days after administration of 131I(100mCi), the therapeutic whole-body scan showed remnant thyroid tissue and bone lesions had no 131I uptake (A: anterior view, B: posterior view). Abstract Polyostotic fibrous dysplasia associated with differentiated thyroid carcinoma was not common. We should avoid misdiagnosis as bone metastases. We reported a case about low thyroglobulin after thyroidectomy associated fibrous dysplasia. Figure 1: A 45-year-old female patients with differentiated thyroid carcinoma. How to cite this article: Liu Xiao, Hong Mei Zhu and Lin Li. Extensive Polyostotic Fibrous Dysplasia Associated with DTC Evaluated With 99m tc-MDP and 131 I Whole Body Scan.