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In utero exposure to Onchocerca volvulus: relationship to subsequent infection intensity and cellular immune responsiveness
1996
Infection and Immunity
Afro-Ecuadorian individuals from an area where Onchocerca volvulus is hyperendemic have been monitored for infection over the past 16 years. To determine whether in utero exposure to O. volvulus biases a child's subsequent immune responses, children (9 to 16 years old) for whom the mother's infection status was known were chosen for study. Children of infected mothers (n ؍ 19) had significantly higher levels of skin microfilariae than children of uninfected mothers (n ؍ 13; P ؍ 0.021).
doi:10.1128/iai.64.12.5061-5065.1996
fatcat:sfaz6meob5gr5jo52uf22odfuq