Many coronaviruses causing a variety of pathological disease in animals and maintained their cycle in nature and causing zoonotic infections, allowing them for genetic recombination, resulting in novel viruses. COVID-19 is the third coronavirus to emerge in the human population in the past 18 years after Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is an outbreak in 2002 and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) outbreak in 2012. Severe acute respiratory

more »

... e coronavirus 2 (SARS-CoV-2, previously known as novel coronavirus or 2019-nCoV is the sixth emerging viral zoonotic disease from China at the end of 2019 and it is a threat to a million of people across the world and a reason for death of hundred thousand of peoples across the globe. Based on evidence, it has mean incubation period of 6.4 days and transmitted mainly through microdroplets and contact with infected person. Fever, Cough, dyspnea, and fatigue are the most common symptom of the patients. Reports also indicated that underlying diseases such as cardiovascular disease, hypertension, and diabetes mellitus further precipitating the condition and more mortality cases were recorded. Even though there is no effective treatment against COVID-19, different antibiotic, antiviral (nucleoside analogues, neuraminidase inhibitors, DNA synthesis inhibitors and chloroquine) have been proposed as a potential drug options for COVID-19. Control measures are the best option preventing the spread of the infection and reduced the incidence of new cases. Therefore, close monitoring of the situation and a coordinated global response is desperately needed to prepare health systems to meet this unprecedented challenge.