Biochemical alterations of inflammatory markers in experimentally induced diabetes in rats

El-Regily F.Y., El-Hindawy M., Sadek M., Abd El-Maksoud A.
2016 Benha veterinary medical journal  
This study was evaluated the protecting effect of rutin on the glycemic condition, lipid profile, in streptozotocin (STZ)-induced experimental diabetic in rats. With respect to an orally administrated rutin on serum glucose, the result is showing a significant decrease in glucose concentration when compared to diabetic group, While, a significant increase in insulin concentration when compared to diabetic. Moreover, the results revealed that, an administration of streptozotocin (STZ) showing
more » ... nificant increase in triacylglycerol, total cholesterol, LDL-c and VLDL-C concentration when compared with control group, while, showing significant decrease in HDL-C concentration and serum AST and ALT activity when compared to the control group. The data revealed also significant increase in serum L-MDA concentration. While, significant decrease in serum calcium concentration when compared to the control group.
doi:10.21608/bvmj.2016.31341 fatcat:mvfecdsos5etffsb5zg7wxldba