This study was evaluated the protecting effect of rutin on the glycemic condition, lipid profile, in streptozotocin (STZ)-induced experimental diabetic in rats. With respect to an orally administrated rutin on serum glucose, the result is showing a significant decrease in glucose concentration when compared to diabetic group, While, a significant increase in insulin concentration when compared to diabetic. Moreover, the results revealed that, an administration of streptozotocin (STZ) showing

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... nificant increase in triacylglycerol, total cholesterol, LDL-c and VLDL-C concentration when compared with control group, while, showing significant decrease in HDL-C concentration and serum AST and ALT activity when compared to the control group. The data revealed also significant increase in serum L-MDA concentration. While, significant decrease in serum calcium concentration when compared to the control group.