Nanotechnology is a branch of science that basically deals with synthesi of nano-size particles. A nanoparticle is an ultrafine particle, or a tiny particle that ranges between 1 to 100 nanometers in size and is undetectable by the human eye. Nanoparticles types are commonly divided into two main groups:- organic and inorganic Organic groups include lipsones, hybrid, micelles, dendriners and compact polymeric nanoparticles. Inorganic group includes quantum dots, silica,fullernes and metal

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... rticle. Artificial nanoparticles can be created from any solid or liquid material, including metals, dielectrics, and semiconductors. Nanoparticles have other physical properties that must be measured for a complete description such as size, shape, dispersion state,surface properties and crystallinty.In the current research work, collected some water from fish area and analyse bacteria responsible for spoilage of fish which are pseudomonas,Escherichia coli,Achromobacter,Serratia, Micrococcus,Staphylococcus aureus.Then isolate bacteria for suitable media (MSA,NAM ).Organic acid and bacteriocins from bacteria showed good antimicrobial activities against spoilage bacteria.Plant derived antimicrobials could prolong fish shelf life and decrease lipid oxidation.Nanoparticles were synthesized of mainly Zinc,Copper,Magnesium,Silver and their characterization were done using UV visible spectrophotometer,Zeta potential, PSA(Particle size Analyser).Different ice crystal of different nanoparticles of Zn,Ag,Mg,Cu shows to prolong the shelf life of fish.Hence nanoparticles can be a great source for preserving and enhancing the shelf life of fish.