Metabolic syndrome in obese adolescents: what is enough?

Leticia Esposito Sewaybricker, Maria Ângela R.G.M. Antonio, Roberto Teixeira Mendes, Antonio de Azevedo Barros Filho, Mariana Porto Zambon
2013 Revista da Associação Médica Brasileira  
Obesity Triglycerides Adolescents A B S T R A C T Objective: To study the agreement among three distinct criteria for metabolic syndrome (MS) adapted to adolescents, and to identify associated factors for MS. Methods: Cross-sectional study with 65 obese subjects aged 10 to 18 years, attended to at the Outpatient Clinic for Obese Children and Adolescents at the Clinical Hospital of the Universidade Estadual de Campinas (Unicamp). MS was defined using the criteria of the World Health Organization
more » ... (WHO), the International Diabetes Federation (IDF), and the Adult Treatment Panel III (ATP III). Clinical, anthropometrical, and laboratorial data were associated to MS. Results: From the 65 subjects, none had MS according to the WHO criteria, while 18 were diagnosed with MS (27.6%) according to the IDF, and 19 (29.2%) according to the ATP III. Agreement between IDF and ATP III was excellent (kappa 81%). In this study, puberty and triglycerides levels showed significant statistical difference when comparing subjects with and without MS, the first for ATP III (p = 0.03), and the second for IDF (p = 0.005) and ATP III (p = 0.001) criteria. Conclusion: The WHO criteria does not seem to be adequate for adolescents. IDF and ATP III criteria had an excellent agreement. Puberty and triglycerides were associated with MS. Objetivo: Avaliar a correlação de três critérios de síndrome metabólica (SM) para adolescentes e identificar fatores associados. Métodos : Estudo transversal com 65 pacientes obesos entre 10 e 18 anos do Ambulatório de Crianças e Adolescentes Obesos do HC-Unicamp. SM foi definida de acordo com a Organização Mundial da Saúde (OMS), International Diabetes Federation (IDF) e Adult Treatment Panel III (ATP III). Buscaram-se fatores associados a SM em dados clínicos, antropométricos e laboratoriais. Resultados: Dos 65 pacientes, nenhum foi diagnosticado como SM pela OMS, sendo 18 (27.6%) pelo IDF e 19 (29.2%) pelo ATP III. A correlação entre IDF e ATP III foi excelente Palavras-chave: Síndrome metabólica Obesidade Triglicérides Adolescentes estatisticamente significativa entre pacientes com e sem SM, sendo a primeira para o ATP III (p = 0.03) e o segundo para IDF (p = 0.005) e ATPIII (p = 0.001). Conclusão: O critério da OMS não parece ser adequado para adolescentes. Há correlação excelente entre os critérios do IDF e ATP III. Puberdade e triglicérides foram fatores associados à SM.
doi:10.1590/s0104-42302013000100013 pmid:23440144 fatcat:6kgzbk3screctofrq4ggnpxqum