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Immunological Study of RSV-induced Mouse Brain Tumor
Brain tumor was induced with Rous sarcoma virus (RSV) in adult inbred mice of A/J as a model of human malignant brain tumor. This brain tumor could not be transplanted to allogenic mice of C3H/He and BALB/c. Moreover, the syngeneic animals which had undergone surgical removal, did not take the secondary challenge of the same tumor cells. These results suggest the presense of the tumor specific transplantation antigen (TSTA) associated with major histocompatibility complex (MHC). The tumordoi:10.2176/nmc.19.355 pmid:86973 fatcat:zyzilqlvuvguvgu3vfiuczdmhu