PHARMA SCIENCE MONITOR AN INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS: AN EMERGING INFECTIOUS DISEASE

Rohan Ghodake, Rishikesh Babar, Sandeep Patil, Kiran Wadkar, Nilofar Naikwade
2011 unpublished
Crimean-Congo Hemorrhagic Fever (CCHF) is a viral zoonotic tick-born disease with a mortality rate of up to 50% in humans. The CCHF Virus (CCHFV) is from the genus Nairovirus and family Bunyaviridae. After a short incubation period, the disease is characterized by sudden fever, chills, severe headache, dizziness, back, and abdominal pain. In severe cases, hemorrhagic manifestations, ranging from petechiae to large areas of ecchymosis develop. CCHF is transmitted to humans by the bite of
more » ... the bite of infected tick and by direct contact with blood or tissue from infected humans and livestock. Since from 1999, establishment of a surveillance and laboratory detection system on viral hemorrhagic fevers particularly on CCHF has had benefits. One of which is the fact that a mortality rate approaching 6% in the year 2007. The present article reviews on the epidemiological and clinical features of CCHF; moreover, treatment, prevention and control strategies with a special focus on oral Ribavirin as a choice of medical treatment.
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