A new technique of epidural and intrathecal catheterization to evaluate pharmacokinetics of epidural administration in dogs: a prospective study [post]

2019 unpublished
Compared to the conventional oral or intravenous drug administration, epidural administration of drugs has significantly higher efficacy and safety. Experimental research on animals should be performed before applying to humans. Unlike the existing canine model, we describe a new and alternative technique of epidural and intrathecal catheterization to investigate the efficacy and safety of epidural drug administration in dogs. Methods: Twelve adult dogs were used in this study. The procedures
more » ... y. The procedures were performed with dogs in sternal recumbency under deep sedation. Epidural
doi:10.21203/rs.2.9257/v1 fatcat:td6q6jgq6zdbxeikuizihiephy