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Formulation and characterization of artemether-loaded sodium alginate microcapsules
Tropical Journal of Pharmaceutical Research
Purpose: To increase the solubility of artemether (ART) in Transcutol® HP through microencapsulation in sodium alginate polymer to achieve sustained in vivo release.Method: Graded concentrations of ART (0.00, 0.25, 0.50, 0.75, and 1.00 g) microcapsules were produced using Tween® 80 by the cold homogenization method at 24 x 1000 rpm for 15 min. Characterization based on yield, encapsulation efficiency (EE), particle size, pH stability, differential scanning calorimetry (DSC), Fourier transformdoi:10.4314/tjpr.v19i7.1 fatcat:34aej32ng5g6dmtv3rlyci44fi