Neurological and neuropsychiatric manifestations and complications of SARS-CoV-2 infection: a narrative review and a case presentation in a previously healthy young white adult

O.Yе. Fartushna, H.V. Palahuta, S.K. Yevtushenko
2021 INTERNATIONAL NEUROLOGICAL JOURNAL  
Background. As the second wave of COVID-19 occurred, it has become clear that a novel coronavirus (SARS-CoV-2), which has consequently sparked a global pandemic, was evolved into wide-ranging multi-organ disease. However, neurological features of COVID-19 infection, especially in young previously healthy adults, have not been widely reported. We aimed to provide a narrative review of the neurological and neuropsychiatric manifestations and complications of SARS-CoV-2, supported with a clinical
more » ... ed with a clinical case presentation. Materials and methods. A comprehensive electronic literature search was performed on Scopus, PubMed, Embase, Cochrane database, World Health Organization database, Ovid, and Google Scholar in accordance with Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines to identify the articles that discussed the neurological and neuropsychiatric presentations of SARS-CoV-2/COVID-19. The neurological manifestations and complications of COVID-19 are illustrated with the clinical case presentation in a previously healthy white young adult. Results and conclusions. Neurological and neuropsychiatric manifestations and complications of SARS-CoV-2 infection range from mild symptoms, such as headache, to catastrophic symptoms, including but not limited to delirium, manic episodes, schizophrenia, stroke, acute hemorrhagic necrotizing encephalopathy, transverse myelitis, encephalitis, meningitis, and Guillain-Barré syndrome. We provided a narrative review of the neurological and neuropsychiatric manifestations and complications of SARS-CoV-2 infection, illustrated with the clinical case presentation in a previously healthy white young adult.
doi:10.22141/2224-0713.17.1.2021.226914 fatcat:7rvln4766vgpnhamxkkivl2ii4