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Substantial progress has been made in human genetics and genomics research over the past ten years since the publication of the draft sequence of the human genome in 2001. Findings emanating directly from the Human Genome Project, together with those from follow-on studies, have had an enormous impact on our understanding of the architecture and function of the human genome. Major developments have been made in cataloguing genetic variation, the International HapMap Project, and with respect todoi:10.1186/1479-7364-5-6-577 pmid:22155605 pmcid:PMC3525251 fatcat:h5dzbsxxuzgpfn7egl25fez3oi