IgA Nephropathy and Psoriatic Arthritis that Improved with Steroid Pulse Therapy and Mizoribine in Combination with Treatment for Chronic Tonsillitis and Epipharyngitis

Tomohiro Kaneko, Akiko Mii, Megumi Fukui, Kiyotaka Nagahama, Akira Shimizu, Shuichi Tsuruoka
2015 Internal medicine (Tokyo. 1992)  
A 65-year-old man was admitted to our hospital with edema and renal dysfunction. He had received a diagnosis of psoriatic arthritis at 50 years of age. As a renal biopsy showed IgA nephropathy (IgAN), bilateral tonsillectomy was performed, and one course of steroid pulse therapy with an oral steroid and mizoribine were subsequently administered. The patient's proteinuria gradually reduced in association with an improvement in the renal function. In addition, the rash and arthralgia were
more » ... ted. In this case, adding treatment for chronic epipharyngitis accelerated the curative effects, and focal infection therapy consisting of immunosuppressive drugs was effective for both IgAN and psoriatic arthritis.
doi:10.2169/internalmedicine.54.3510 pmid:25948353 fatcat:6tiks4zqunagnijdloatdm4hja