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The Filamentous FungusAspergillus nigerContains Two "Differentially Regulated" Trehalose-6-phosphate Synthase-encoding Genes,tpsAandtpsB
Journal of Biological Chemistry
Two genes encoding trehalose-6-phosphate synthase were cloned from Aspergillus niger. tpsA was cloned using the Saccharomyces cerevisiae GGS1/TPS1 gene as a probe. It encodes a 517-amino acid polypeptide with 64 -70% similarity to trehalose-6-phosphate synthase of S. cerevisiae, Kluyveromyces lactis, and Schizosaccharomyces pombe. Its transcription occurs constitutively and is enhanced on carbon-derepressing carbon sources, coinciding with the presence of a CreA-binding nucleotide motif in thedoi:10.1074/jbc.272.5.2729 pmid:9006911 fatcat:zqti3lewp5f3php54ya5m2zlc4