Accuracy of VSRAD Analysis Using Scout Images: Comparison with Conventional 3D-T1WI

Tatsuya Katayama, Keita Watanabe, Hidekuni Narimatsu, Shingo Kakeda, Yukunori Korogi
2021 Japanese Journal of Radiological Technology  
The voxel-based specific regional analysis system for Alzheimer's disease (VSRAD), which targets volume loss in medial temporal lobe, was developed as a sensitive diagnostic tool to detect early stages of Alzheimer's disease. However, conventional three-dimensional T1 -weighted image (3D-T1WI) for VSRAD analysis acquires relatively long acquisition time. Recently, it became possible to acquire Scout images (Scout) for positioning as a 3D image in a short time. The aim of this study was to
more » ... ine whether Scout was reliable in VSRAD. We measured voxel-based analysis of gray matter volume using VBM and Z-score of medial temporal lobe atrophy using VSRAD advance 2 from conventional 3D-T1WI and Scout. It showed significantly different gray mass between conventional 3D-T1WI and Scout. However, there was no significant difference in Z-score (p=0.41). The Z-scores measured from Scout and conventional 3D-T1WI were significantly correlated (r=0.96, p<0.05). There is a possibility that Scout can be used to detect brain morphometry abnormalities instead of conventional 3D-T1WI in the VSRAD analysis.
doi:10.6009/jjrt.2021_jsrt_77.12.1411 pmid:34924477 fatcat:6slpcjvq45fzxhstd7svyv46qe