In order to evaluation the best double cropping system in Golestan province, an experiment was carried out in 2010 in Karkandeh region (Kord kuy) in a split plot design based on RCBD with two factors and four replications. Main plots were winter crop (wheat, pea, canola, bean and fallow) and subplots were two cotton cultivars (Golestan and Sepid). Some agronomical, linter quality and cotton disease measured in this study. Analysis of variance indicated that, winter crop and cotton cultivars had

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... significant effect on bolls number, bolls weight, earliness, total yield and linter quality. The effects winter crop significant differences on the disease damping and verticillium. The most plant disease damping off percent in pea (%16.37) and decreasing in wheat (% 6.25) were showed. The most plant disease verticillium percent in fallow (%13.45) and decreasing in wheat (% 5.75) were showed.