Polymer Based Wafer Technology: A Review

Lade Milind, Payghan Santosh, Tamboli Zaki, Disouza John
2013 International Journal of Pharmaceutical & Biological Archives   unpublished
At all the times there are rising hassle for developing a dosage form which improve patient convince and compliance particularly for Oral/ Buccal drug delivery system. Due to small size, little dose, thickness of buccal wafer over other dosage form is most acceptable and pleasant. Flash release oral wafer drug delivery system is an alternative approach for the tablets, capsules, and liquid oral dosage forms for pediatric and geriatric patients. Effective attachment with buccal layers represents
more » ... Buccal wafers as convenient and suitable dosage form compared to others. The semi-synthetic and synthetic natural polymer as film former in low concentration can be used for the preparation of Buccal wafers and hence such dosage form are easy to handle, cost effective, fast absorbable, non-irritating and mostly preferred by patient. It improve the efficacy of APIs by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. Wafers formulations are appropriate in allergenic conditions, cough and cold remedies, sore throat, nausea, pain and CNS disorders. Present article overview the advancement in the oral dosage forms, application, formulation composition, method of preparation, evaluation and marketed products of oral flash release wafers.
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