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Synthesis of 3,4-Dihydropyrido (3,4-b) benzindoles using Polyphosphate Ester as a Cyclising Agent
1975
Zenodo
Department of Chemistry, Kamatak University Post-Graduate Centre, Gulbarga-585105 Manuscript received 7 April 1975; revised 7 July 1975; accepted 15 July 1975. β-[Benz(e)- and benz(g)indo1-3-yl[ethylamines have been reacted with benzoyl chloride, acetic anhydride and formamide to yield the respective amides. These amides have been cyclised with polyphosphate ester (PPE) to the corresponding 1-substituted 3,4-dihydropyrido-(3,4-b)benzin doles (β-carbolines) in 60--70% yields.
doi:10.5281/zenodo.6411248
fatcat:ebleogqttvanbjc76himjrui54