Polymorphism of the inhibin βA gene and its relationship with superovulation traits in Chinese Holstein cows

W.C. Yang, S.J. Li, L. Chen, L.G. Yang
2014 Genetics and Molecular Research  
Inhibin is a major regulator of secretion of folliclestimulating hormone, which is involved in follicular development and regulation of steroidogenesis in females. The objectives of this study were to detect polymorphisms of the bovine inhibin beta-A subunit (INHβA) gene and to evaluate its associations with superovulatory responses in 171 Chinese Holstein cows treated for superovulation. Polymerase chain reaction-restricted fragment length polymorphism revealed a C>T transition determining the
more » ... StyI polymorphism at position 7639 in intron I of the bovine INHβA gene, and three genotypes (CC, CT, and TT) were detected. The frequencies of the three genotypes showed a tendency for CT > TT > CC, and this polymorphism was in Hardy-Weinberg equilibrium. Statistical analysis revealed no significant differences of least square means for superovulation traits among the three genotypes (P > 0.05). These results demonstrate, for the first time, ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 13 (1): 269-275 (2014) W.C. Yang et al. that the detected loci of the INHβA gene have no significant effects on superovulation performance in Chinese Holstein cows.
doi:10.4238/2014.january.17.11 pmid:24535853 fatcat:5mvp2bx4k5d3plidltdofry6li