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A Method to Constrain Genome-Scale Models with 13C Labeling Data
<span title="2015-09-17">2015</span>
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Current limitations in quantitatively predicting biological behavior hinder our efforts to engineer biological systems to produce biofuels and other desired chemicals. Here, we present a new method for calculating metabolic fluxes, key targets in metabolic engineering, that incorporates data from 13 C labeling experiments and genome-scale models. The data from 13 OPEN ACCESS Citation: García Martín H, Kumar VS, Weaver D, Ghosh A, Chubukov V, Mukhopadhyay A, et al. (2015) A Method to Constrain
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... nome-Scale Models with 13 C Labeling Data. PLoS Comput Biol 11(9): e1004363.
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