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The development of single, daily dose antibiotic regimens and the availability of computerized ambulatory infusion pumps have made it possible for most patients with infectious endocarditis (IE) to complete their treatment in an outpatient setting. This review summarizes the current literature on the classification, diagnosis, clinical and laboratory manifestations, and inpatient and outpatient management of IE. An algorithmic approach to the diagnosis and management of IE is proposed. Mostdoi:10.1155/2000/590871 fatcat:5t3s2jxxy5e4vfcobjajkvkk6q