Elizabeth Rodríguez-Carranco, Ramírez-Segura, Sandra Paredes-Fernández, Julia, Genaro-Sierra, Roberto García, Navarrete
ARTICLE INFO ABSTRACT Primary central nervous system tumors originate from the neuroepithelial tissue, being the most common the gliomas. Nonspecific symptoms can include a headache, seizures, pyramidal syndrome and disorders of mental functions. Imaging studies provide critical information for the characterization of the location extension and other radiological features. The study of these neoplasms with nuclear medicine allows assessing more accurately the biological component of the lesion.
more » ... nent of the lesion. Through the use of multimodal neuronavigation systems, it is possible to perform the integration of these different types of diagnostic imaging, increasing the precision and safety of surgical procedures. We present the case of a patient with a diffuse glioma of the right frontal lobe with a pyramidal syndrome which was operated by awake-craniotomy and multimodal neuronavigation-assistance. Currently, at 36 months of follow-up, the patient has full clinical recovery and no evidence of disease on PET scan. Copyright©2018, Elizabeth Rodríguez-Carranco. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. INTRODUCTION Clinical Case A 17-year-old female who is evaluated for a condition of at least two weeks of evolution characterized by a decrease in the strength of the left half of the body and ipsilateral hypoesthesia. On physical examination, a left pyramidal syndrome was integrated. Imaging studies were performed and the diagnostic possibility of a diffuse glioma was considered due to the findings. Nuclear medicine studies with FET were requested and the diagnostic possibility of a diffuse glioma was considered. The patient was scheduled to undergo surgery to resect the lesion byawake-craniotomy. Transoperative neuropsychological evaluation and 3D ultrasonographic reconstruction were performed to guide the resection with a BrainLab® neuronavigation system.