Metallic and non metallic nanoparticles incorporated meropenem and ceftazidime synthesis for the improved antibacterial activity against human pathogenic bacteria

S Karthick, Raja Namasivayam, Varinder Singh, S Samydurai
2014 Scholars Research Library Der Pharma Chemica   unpublished
In the present study improved antibacterial activity of meropenem and ceftazidime incorporated with free and chitosan coated egg albumin nanoparticles, silver nanoparticles against Escherichia coli and Salmonella paratyphi has been carried out. Egg albumin nanoparticles incorporated drugs were synthesized by coacervation method and chitosan coated nnao drug conjugate by ionic gelation method. Synthesized nano drug conjugates were characterized by scanning electron microscopy (SEM),energy
more » ... ive x ray spectroscopy (EDX) and Fourier Transform Infrared spectroscopy (FTIR).All the nanoformulations showed distinct antibacterial activity against both the tested bacteria and further studies will be helpful to formulate in bulk volume and commercialization possible through proper clinical trials