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Conjugated heat transfer and hydraulic performance for nanofluid flow in a rectangular microchannel heat sink with LVGs (longitudinal vortex generators) are numerically investigated using at different ranges of Reynolds numbers. Three-dimensional simulations are performed on a microchannel heated by a constant heat flux with a hydraulic diameter of 160 μm and six pairs of LVGs using a single-phase model. Coolants are selected to be nanofluids containing low volume-fractions (0.5%–3.0%) of Al2O3doi:10.31224/osf.io/z65vx fatcat:7staocmdqzbknaazdxprbyhtmi