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Animal Pain Models for Spinal Cord Stimulation
Animal Models in Medicine and Biology [Working Title]
Spinal cord stimulation (SCS) is an electrical neuromodulation technique with proven effectiveness and safety for the treatment of intractable chronic pain in humans. Despite its widespread use, the mechanism of action is not fully understood. Animal models of chronic pain, particularly rodent-based, have been adapted to study the effect of SCS on pain-like behavior, as well as on the electrophysiology and molecular biology of neural tissues. This chapter reviews animal pain models for SCS,doi:10.5772/intechopen.96403 fatcat:ge7764xvl5hp7c7xbwwc7kqhnm