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Evaluation of the serum-free light chain test in untreated patients with AL amyloidosis
2008
Haematologica
Preserved Fulltext
We evaluated the Serum Free Light Chain (FLC) test in a series of 133 untreated patients with systemic AL amyloidosis. The FLC test detected the monoclonal gammopathy in 87% compared with 92% for immunofixation of serum and urine in combination. However, both tests proved complementary. The FLC test was also a valuable tool in patients with advanced renal failure in spite of uninvolved light chain retention. Higher FLC levels were associated with higher bone marrow plasmocytosis, poorer
doi:10.3324/haematol.11687
pmid:18287137
fatcat:w6d7isd7dvcebj7ckpv5m5tk4i