Hypoxic-Ischaemic Encephalopathy and the Blood-Brain Barrier in Neonates

Wei Ling Amelia Lee, Adina T. Michael-Titus, Divyen K. Shah
2017 Developmental Neuroscience  
nents of the NVU, e.g., astrocytes and pericytes, to the maintenance of this physiological barrier. We also explore the development of therapeutic options in HIE, such as harnessing the transport systems in the BBB, to enable the delivery of large molecules with molecular Trojan horse technology, and the reinforcement of the physical barrier with cell-based therapy which utilizes endothelial progenitor cells and stem cells.
doi:10.1159/000467392 pmid:28434009 fatcat:pvbz32dhdfeu7ejn6k4m3h2lkq