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Derivative Spectrophotometric Methods for the Determination of Bendamustine Hydrochloride
Journal of Applied Pharmaceutical Science
Bendamustine hydrochloride is used to treat chronic lymphocytic leukemia. It kills the existing cancer cells and limits the growth of new cancer cells. Three simple, rapid and sensitive spectrophotometric methods were developed for the determination of Bendamustine hydrochloride in phosphate buffer (pH 8.0) (Method A) and boric buffer (pH 9.0) (Method B). Method C is a difference spectroscopy technique in which the amplitude was chosen for the analytical calculations. Bendamustine hydrochloridedoi:10.7324/japs.2012.21126 fatcat:52g2dkeeovarfkfdnsuxzexzma