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Acid-induced cell injury and death in lung epithelial cells is associated with the activation of mitogen-activated protein kinases
2013
Molecular Medicine Reports
Gastric hydrochloric acid (HCl) has been regarded as a causative factor of acute lung injury (ALI). The activation of mitogen-activated protein kinases (MAPKs) has been suggested to be a mechanism involved in the pathogenesis of ALI in vivo. However, the effects of HCl on MAPK activation in lung epithelial cells remain to be fully elucidated. Further investigation into the role of MAPK activation in acid-induced cell injury and death is also needed. In the present study, BEAS-2B cells were
doi:10.3892/mmr.2013.1537
pmid:23784034
fatcat:gfa67z6vt5hpvf6nwcmg7vyqni