Regional innovation network has become an important way to improve national independent innovation ability and promote regional and social development. This paper studies the evolution of the synergetic innovation system of industry-university-Research Collaboration under the government behaviour, constructs an asymmetric evolutionary game model between the government and industry-university Research collaboration, and analyses the influence of parameter changes on synergetic innovation

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... making behaviour. The results showed that the government's regulatory costs, subsidies from the government, the production, will take the profit resulting from the synergetic innovation behavior, coordination costs and government punishment, and one party to the cooperative behaviour decision to bring the other side of the loss factors such as size, to participate in Innovation decision-making behaviour of the subject of dynamic evolution path and the results have important influence to the use of MATLAB software evolution paths of related factors under different conditions and the trend of simulation test and verify.