Correlation of myocardial p-(123)I-iodophenylpentadecanoic acid retention with (18)F-FDG accumulation during experimental low-flow ischemia

Cindy Q Shi, Lawrence H Young, Edouard Daher, Edward V R DiBella, Yi-Hwa Liu, Eliot N Heller, Sami Zoghbi, Frans J Th Wackers, Robert Soufer, Albert J Sinusas
2002 Journal of Nuclear Medicine  
Myocardial ischemia is associated with reduced free fatty acid (FFA) beta-oxidation and increased glucose utilization. This study evaluated the potential of dynamic SPECT imaging of a FFA analog, p-(123)I-iodophenylpentadecanoic acid (IPPA), for detection of ischemia and compares retention of IPPA with (18)F-FDG accumulation.
pmid:11884504 fatcat:husd4ekluvd23nnem2qv7srhmq