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Homogeneous Crystal Nucleation Near a Metastable Fluid-Fluid Phase Transition
2012
Physical Review Letters
Several scenarios exist for the protein crystallization and aggregation in solutions near a metastable fluid-fluid phase separation below the solubility line. Based on computations, it was proposed that the fluid-fluid critical point enhances the crystallization rate by many orders of magnitude, while, based on experiments, it was proposed that the fluid-fluid spinodal controls the crystallization rate. Using molecular dynamic simulations for an isotropic model with sticky interaction, we show
doi:10.1103/physrevlett.109.095702
pmid:23002854
fatcat:zwj2wo5c7rgqtgabvyct6yqgnq