The escape of toxic and harmful gases is a common disaster effect in tunnel engineering. Frequent drilling and blasting excavation disturbances under high in-situ stress environment will inevitably lead to cumulative damage effect on surrounding rock, which will increase the permeability coefficient of surrounding rock, increase the risk of toxic and harmful gas escape, and seriously endanger construction safety. In this paper, based on real-time monitoring data of harmful gases during blasting

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... and excavation of Yuelongmen Tunnel on Chengdu-Lanzhou Railway, this study summarized laws and distribution characteristics of harmful gas escape intensified by the blasting excavation, and the effectiveness of shotcreting and grouting for water blocking to inhibit gas escape is verified. Then, taking water-containing and gas-containing voids as carriers, considering the influence of different in-situ stress, explosion load and void parameters (including void pressure, void diameter and distance between void and tunnel), to carry out research on the escape mechanism of water-soluble (H 2 S) and insoluble (CH 4 ) toxic and harmful gases under the coupling effect of stress-seepage-damage. The relationship between the amount of harmful gas escaped and the damage degree of the surrounding rock of the tunnel is analyzed, and the functional relationship between it and the in-situ stress, explosion load and cave parameters is established. The results further demonstrate that the amount of escaped harmful gases, such as methane and H 2 S is closely related to lithology of surrounding rock, occurrence conditions of the deep rock mass, development degree of structural fractures and void parameters. The damage of surrounding rock caused by dynamic disturbance during blasting excavation is the main reason of aggravating harmful gas escape. The research results can provide a theoretical reference for preventing harmful gas from escaping in the similar engineering construction.