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Disease-Associated Circular RNAs: From Biology to Computational Identification
2020
BioMed Research International
Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed continuous loop, generated through various backsplicing events of pre-mRNA. An accumulating number of studies have shown that circRNAs are potential biomarkers for major human diseases such as cancer and Alzheimer's disease. Thus, identification and prediction of human disease-associated circRNAs are of significant importance. To this end, a computational analysis-assisted strategy is indispensable to detect, verify, and
doi:10.1155/2020/6798590
pmid:32908906
pmcid:PMC7450300
fatcat:ggwwamht4ng4zgtqdqs3shjvk4