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The comparison of teratogenic and carcinogenic effects of some carbamate compounds
Ethyl carbamate and a series of related compounds were given in single intraperitoneal doses to pregnant Syrian hamsters on Day 8 of gestation, and fetuses were examined for malformations on Day 13 of gestation. Urethan produced a variety of malforma tions and growth retardation. Of the compounds modified in the carboethoxy end, n-propyl carbamate was as teratogenic as the ethyl carbamate, and /3-hydroxyethyl carbamate had only bor derline effect, while allyl carbamate and n-butyl carbamatepmid:6051281 fatcat:b52mxv76wfetvgbnprey547t6i