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The Emerging Target Protein Tyrosine Phosphatase 1B (PTP1B) for Type 2 Diabetes Mellitus Management
2022
Journal of Diabetes and Clinical Research
Preserved Fulltext
Insulin resistance and impaired insulin secretion by β cells are the key defects in type 2 DM. In fact, insulin resistance is present in muscle, liver, adipose tissue, kidney, gastrointestinal tract, vasculature and brain tissues, and pancreatic β cells. Multiple abnormalities can lead to the development of insulin resistance in target tissues, such as defects involving insulin
doi:10.33696/diabetes.3.048
fatcat:gbh4gbv7svb6njtgp6cyvnwefq