The biosynthesis of hyaluronic acid by group A Streptococcus. VI. Biosynthesis from uridine nucleotides in cell-free extracts

A MARKOVITZ, J A CIFONELLI, A DORFMAN
1959 Journal of Biological Chemistry  
Previous studies have demonstrated that both the glucosamine and glucuronic acid moieties of hyaluronic acid synthesized by Group A streptococci are derived from glucose without previous scission of the glucose molecule (1) . Shortly after the discovery by Caputto et al. (2) of the role of uridine diphosphoglucose in the epimerization of glucose, Park (3-5) noted the accumulation of uridine nucleotides in penicillin-inhibited by guest on March 24, 2020 http://www.jbc.org/ Downloaded from
pmid:14421284 fatcat:r2fli7wndbcdtnbdruygxm4m6e