Synthesis and Properties of Conjugates between Silver Nanoparticles and DNA-PNA Hybrids

Gennady Eidelshtein, Shay Halamish, Irit Lubitz, Marcello Anzola, Clelia Giannini, Alexander Kotlyar
2013 Journal of Self-Assembly and Molecular Electronics  
We describe the preparation and properties of a stable conjugate between two 15 nm silver nanoparticles (AgNPs) and a DNA-PNA hybrid composed of 10 guanine-cytosine base pairs. We show that the conjugate is spontaneously formed during incubation of a DNA-PNA hybrid, containing phosphorothioate residues at both ends of the DNA strand with AgNPs. The conjugate molecules were separated from individual AgNPs and multiparticle structures by gel electrophoresis. We demonstrate that the absorption
more » ... trum of the conjugate is broader than that of AgNPs, due to the interparticle plasmon coupling.
doi:10.13052/same2245-4551.113 fatcat:i3eljd7d2vg3plfkkfer6rjnbi