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DNA Methylation Profiles and Their Diagnostic Utility in BC
2019
Disease Markers
Biomarkers, including DNA methylation, have shown a great potential for use in personalized medicine for BC and especially for the diagnosis of BC in developing countries. According to the bisulfite sequencing PCR in twelve specimens (BC and matched normal tissues), nine genetic probes were designed to detect the frequency of methylation of the promoters in a total of 302 paired cases of BC and matched normal breast tissues. Finally, a total of 900 serum samples were used to validate the use of
doi:10.1155/2019/6328503
fatcat:lncgqjjgdvfxxh3iyeys6x5fam