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Ribavirin suppresses bacterial virulence by targeting LysR-type transcriptional regulators
2016
Scientific Reports
Supplementary movie Dynamic interaction of ribavirin within AphB co-inducer/ligand binding site, as evident from 20ns molecular dynamic simulation. Supplementary figure S1. Ribavirin does not alter the expression of AphB of N16961 wt (a) and Hrg of S. Typhi Ty2 strains in vitro as shown by western blot: Bacterial strains, N16961 (a) and S. Typhi Ty2 (c) were cultured in AKI media or LB at 37°C with shaking in the presence of increasing concentrations of ribavirin.
doi:10.1038/srep39454
pmid:27991578
pmcid:PMC5171790
fatcat:xuhx3v7mlzbx5l3pimcurycw6m