A systematic review protocol of medical and clinical research landscapes and quality in Malaysia and Indonesia [REALQUAMI]
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Boon How Chew, Shaun Wen Huey Lee, Poh Ying Lim, Soo Huat Teoh, Aneesa Abdul Rashid, Navin Kumar Devaraj, Adibah Hanim Ismail @ Daud, Abdul Hadi Abdul Manap, Fadzilah Mohamad, Aaron Fernandez, Hanifatiyah Ali, Puteri Shanaz Jahn Kassim
(+4 others)
2020
unpublished
Background Research landscapes and quality may change in many ways. Much research waste has been increasingly reported. Poorly conducted clinical and biomedical researches are detrimental to the health of the people and healthcare performance with misleading clinical evidence. Efforts to improve research performance will need good data on the profiles and performance of past research. This systematic review aims to describe the characteristics and examine the quality of clinical and biomedical
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... esearch in Malaysia and Indonesia. Methods A search will be conducted in PubMed, EMBASE, CINAHL and PsycINFO to identify for published clinical and biomedical research from 1962 to 2019 from Malaysia and/or Indonesia. Additional search will also be conducted in MyMedR (Malaysian only). Studies found will be independently screened by a team of reviewers, relevant information will be extracted and the quality of articles will be assessed. In Phase 1, the characteristics of the research including the profiles of the researchers and the journals in which they are published will be reported descriptively. In Phase 2, a research quality screening tool will be validated to assess the research quality based on three domains of relevance, the credibility of the methods and usefulness of the results. Associations between the research characteristics and quality will be analysed. The independent effect of each of the determinant will be quantified in multivariable regression analysis. Longitudinal trends of the research characteristics, health conditions studied and settings, among others will be explored. Discussion Results of this study will serve as the 'baseline' data for future evaluation and within the country and between countries comparison. This review may also provide informative results to stakeholders of the evolution of research conduct and performance from the past until now. The longitudinal and prospective trends of the research characteristics and quality could provide suggestions on improvement initiatives. Additionally, information on health conditions, research settings, and whether they are over- or under-studied may help future prioritization of research initiatives and resources. Registration: CRD42020152907 (PROSPERO) and https://osf.io/w85ce (Open Science Framework's registry for Research on the Responsible Conduct of Research).
doi:10.21203/rs.3.rs-40583/v1
fatcat:qoziksqpnves5fmbz2hlu237ha