Interactomics of Blebbistatin

Miklós Képiró, Boglárka H. Várkuti, György Hegyi, Mihály Kovács, András Málnási-Csizmadia
2013 Biophysical Journal  
extracellular domain (ECD) of CaSR with various spectroscopic methods including the tryptophan fluorescence titration, circular dichroism (CD) and nuclear magnetic resonance (NMR) as well as molecular dynamic simulation. These results provide important implications for our understanding of how the CaSR integrates information about these two completely different classes of agonists-an inorganic divalent cation, and another hand, a nutrient-how the receptor senses these agonists in healthy and diseased states.
doi:10.1016/j.bpj.2012.11.2252 fatcat:ln3pjsxi2fcsfcp4ta5cam4g6a