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Vertebrate Paralogous Conserved Noncoding Sequences May Be Related to Gene Expressions in Brain
2012
Genome Biology and Evolution
Vertebrate genomes include gene regulatory elements in protein-noncoding regions. A part of gene regulatory elements are expected to be conserved according to their functional importance, so that evolutionarily conserved noncoding sequences (CNSs) might be good candidates for those elements. In addition, paralogous CNSs, which are highly conserved among both orthologous loci and paralogous loci, have the possibility of controlling overlapping expression patterns of their adjacent paralogous
doi:10.1093/gbe/evs128
pmid:23267051
pmcid:PMC3595034
fatcat:62vidmly3nc6dken5ljmgdjntq