period and I I P.M., he several times slept, and ate an egg without seeming to suffer much uneasiness. Without difficulty, at eleven o'clock, a draught containing in solution thirty grains of chloral hydrate was drunk by the patient. During the night, he slept fairly, with occasional intermissions. In the intervals of sleep, two eggs were eaten, and a good quantity of ice was sucked, from which he derived much relief. Between 2 A.M. and twelve o'clock midnight on the 3Ist, nine thirtygrain

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... of chloral hydrate were given ; the first threeper rectum; the remainder by the mouth. At 3.15 P. M, he ate and drank easily. Early on the morning of June ist, whilst at his breakfast of bread and butter and tea, swallowing was observed to be rather difficult. He was also slightly delirious and excited. Towards noon, the difficulty of swallowing had disappeared. For dinner he ate a mutton-chop, and drank with apparent comfort half a pint of beer. At 7.30 P.M., he was quiet and dozing. Between 4 A.M. and i i P. AI., seven thirtygrain doses of chloral hydrate were taken in milk. The case underwent but little change during June the 2nd.-At 2 A.M., he was very restless, and swallowed with difficulty. As the morning wore on, the