Schlaf und Mild Cognitive Impairment

Nina Müller
2013 unpublished
Mild cognitive impairment (MCI) is an organic brain syndrome thought to be a prodrome of dementia. Subjective cognitive impairment (SCI) has also been linked to an increased risk of developing dementia. It's well known that patients with neurodegenerative diseases suffer from poor sleep quality. Sleep disorders in the elderly may in turn cause a low quality of life, such as impairments of the instrumental activities of daily living (IADL) or a diminished self-rated health (SRH), as well as
more » ... tive deficits. In the present study the results of an investigation of sleep quality and quality of life in MCI and SCI patients will be reported. Further, the outcomes of analyzing the relationship between sleep quality and cognitive functions (attention, executive functions) will be presented. Material und methods 84 MCI and SCI patients of a memory clinic (age: M = 69.24, SD = 8.66) underwent a comprehensive neuropsychological assessment. MCI patients were classified into amnestic (aMCI) and non-amnestic MCI (naMCI), according to their cognitive deficits. Each participant completed a sleep questionnaire (Pittsburgh Sleep Quality Index, PSQI), an IADL questionnaire (Bayer Activities of Daily Living, B-ADL) and a SRH questionnaire (Short-Form Health Survey 36, SF-36). Results Poor sleep quality was linked to low SRH and impairments in IADL. MCI and SCI patients didn't differ in terms of IADL or SRH, nor did aMCI, naMCI or SCI patients. There was no relationship between sleep quality and attention or executive functions. Conclusion Sleep quality and quality of life seem to be related to each other in SCI and MCI patients which is probably due to a broad variety of moderating factors and complex interdependency. The cognitive state appears to have no effect on quality of life and there seems to be no relationship between sleep quality and attention or executive functions as well. Future studies need a more comprehensive design and bigger sample sizes to gain more statistical power and to rule out other influences [...]
doi:10.25365/thesis.28687 fatcat:35qyot7t4zdulfl454kfbk2r4a