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Vehicles of inverted hexagonal liquid crystalline lipid phases self-assembled at room temperature

Borislav Angelov, A. Angelova, V. M. Garamus, S. Lesieur
2013

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Dispersed nonlamellar lipid phases offer one of the most important contemporary ways for the development of newmaterials for drug delivery vehicles. The structure of self-assembled vehicles of an inverted hexagonal type liquid crystalline(LC) lipid phase was investigated by means of small angle X-ray scattering (SAXS), quasi-elastic light scattering (QELS),and cross-polarised light optical microscopy (POM). A notable difference was established between the SAXS patterns of thebulk inverted
more » ... nal (HII) phase and the corresponding nanoparticles (NPs) dispersion. The structure of the hexosomeNPs appeared to be more hydrated than that of the bulk HII phase. Both systems were stable at room temperature.
doi:10.3204/desy-2014-02691 fatcat:tvyj3pm4uzaerezwkch7jyxfki
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Borislav Angelov, A. Angelova, V. M. Garamus, S. Lesieur. "Vehicles of inverted hexagonal liquid crystalline lipid phases self-assembled at room temperature." (2013) 211 – 215 (2013).