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Variation in Genetic Relatedness Is Determined by the Aggregate Recombination Process
2020
Genetics
The genomic proportion that two relatives share identically by descent-their genetic relatedness-can vary depending on the history of recombination and segregation in their pedigree. Previous calculations of the variance of genetic relatedness have defined genetic relatedness as the proportion of total genetic map length (cM) shared by relatives, and have neglected crossover interference and sex differences in recombination. Here, we consider genetic relatedness as the proportion of the total
doi:10.1534/genetics.120.303680
pmid:33109528
pmcid:PMC7768252
fatcat:k2dwce5gdfckdlp5p4q2peqqvi