SCF3 Radical Initiated Cascade Reaction of Unsaturated Hydrocarbon

Yun Shi, Ting Xiao, Dong Xia, Wenchao Yang
2022 Youji huaxue  
Fluorinated compounds have been widely used in pharmaceuticals, pesticides and other disciplines due to their special physical and chemical properties, which motivates the frequent introduction of fluorinated functionalities into lead compounds to improve their physical and chemical properties. The trifluoromethylthio (SCF3) group with high electronegativity and special lipophilicity plays an important role in a multitude of fluorinated compounds. The recent progress in the field of cascade
more » ... tion of unsaturated hydrocarbon initiated by SCF3 radical, including reaction design, reaction mechanism and outlook, is summarized.
doi:10.6023/cjoc202203041 fatcat:6rz6ctf7rvbytet2yesoz3f5ry